lysate amebocyte assay

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Limulus amebocyte lysate — (LAL) is an aqueous extract of blood cells (amoebocytes) from the horseshoe crab, Limulus polyphemus . LAL reacts with bacterial endotoxin or lipopolysaccharide (LPS), which is a membrane component of Gram negative bacteria. This reaction is the… … Wikipedia
Endotoxin — Endotoxins (not to be confused with enterotoxin) are potentially toxic, natural compounds found inside pathogens such as bacteria. Classically, an endotoxin is a toxin which, unlike an exotoxin , is not secreted in soluble form by live bacteria,… … Wikipedia
Depyrogenation — refers to the removal of pyrogens from solution, most commonly from injectable pharmaceuticals. A pyrogen is defined as any substance that can cause a fever. Bacterial pyrogens include endotoxins and exotoxins, although many pyrogens are… … Wikipedia

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